Brain somatic mutations in various components of the mTOR complex 1 (mTORC1) pathway have emerged as major causes of focal malformations of cortical development and intractable epilepsy. While these distinct gene mutations converge on excessive mTORC1 signaling and lead to common clinical manifestations. it remains unclear whether they cause similar cellular and synaptic disruptions u... https://excellentphoto.shop/product-category/firmware/