Cellular and animal experiments and computational fluid dynamics (CFD) have revealed that mechanisms of the initiation. growth and rupture of a cerebral aneurysm are related to hemodynamics. By direct observation of a cerebral aneurysm during craniotomy. thinning or thickening sites can be found on the aneurysmal wall. https://www.roneverhart.com/Hosa-SH-8X4-25-Stage-Box-Non-locking-8x4-25-p37478/