Interactions With Benzodiazepines and Other CNS Depressants Advise patients and caregivers that potentially deadly additive effects may arise if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, which include alcohol, and never to employ these drugs concomitantly Until supervised by a healthcare supplier (see WARNINGS https://codeine.store/product/purple-drank/